Ayahuasca retreats in the Amazon, a journey into the heart of the jungle for authentic and healing experiences.
Explore AmazongWhy choose One Way Ayahuasca retreats
The best and safest Ayahuasca retreat in the world as voted by Eluxe Magazine
For over 20 years, we have been the only Ayahuasca retreat in Manu recognized by the Ministry of Health, ensuring safety and authenticity. Our ceremonies blend ancestral wisdom with modern medicine, guided by Shipibo and Q’ero healers, alongside doctors and psychologists. Rooted in the Inca cosmovision, we honor traditional healing while offering long-term integration tools like Munay meditation. Through our non-profit, HUMAN ACTIONS, we support communities, nature, and animal welfare. Located in the Sacred Valley, just two hours from Machu Picchu, we provide a transformative retreat for deep healing and self-discovery.


4 Day Ayahuasca Retreat Cusco Safari
Learn more6 days Ayahuasca retreat and visit to Manu
Learn moreHuman Actions non profit organisation
One Way Ayahuasca founded Human Actions in 2015, and it quickly became a driving force behind our work. The profound impact of engaging in projects based on Ayni (reciprocity) has transformed our team’s perspective, making social responsibility our core mission. We provide sustainable social assistance, holistic healing, and cultural education, focusing on vulnerable communities in Peru. Our initiatives include community regeneration, animal rescue, and environmental conservation.

Our safety protocols
Your physical & psychological safety is our top priority.
We have carefully designed safety protocols that protect the safety of our guests; physically, emotionally and mentally, both inside and outside the Ayahuasca ceremony. Feeling safe and comfortable will allow you to open up and receive the full benefits of the ceremonies. For that reason, we integrate professional medical staff in our retreats ensuring the safety of guests.
Our safety protocols
Ancestral Healing Experts
We have carefully designed safety protocols that protect the safety of our guests; physically, emotionally and mentally, both inside and outside the Ayahuasca ceremony. Feeling safe and comfortable will allow you to open up and receive the full benefits of the ceremonies. For that reason, we integrate professional medical staff in our retreats ensuring the safety of guests.

What people are saying
Creating the best experience possible for you.
430+ Positive Reviews

Stay in the Heart of Manu – Eco Lodge & Facilities
Our lodge is nestled in the pristine Manu Rainforest, offering an immersive experience in the heart of the Amazon. Surrounded by lush jungle and vibrant wildlife, our eco-friendly accommodations provide comfort while maintaining harmony with nature.